Individuals should consider getting tested for celiac disease if they fall into any of the following categories: adults concerned about having celiac disease, those with a first-degree relative diagnosed with the condition, people with autoimmune disorders such as Type 1 diabetes, autoimmune thyroid disease, or autoimmune liver disease, and individuals with Down syndrome, Turner syndrome, Williams syndrome, or selective IgA deficiency.

Undiagnosed and untreated celiac disease can have serious consequences. Long-term complications include anemia, malnutrition, weak bones, and an increased risk of developing other autoimmune conditions.

This test measures your total IgA levels and checks for IgA antibodies to tissue transglutaminase (tTG). If your IgA levels are low, additional tests will be done to measure IgG antibodies to both tTG and deamidated gliadin peptide (DGP).